Nucleation of Bubbles in DNA
نویسندگان
چکیده
Understanding the thermal denaturation process of DNA provides insight into other biological processes that involve denaturation. Examining bubbles in DNA investigates the intermediate states that exist in this important melting transition. Information can be gathered by studying the impact the location of a defect that will nucleate a bubble has on the amount of bubble states that form. A relationship exists where the closer the defect is to the middle, the less bubble states that form. Further investigation found that the nature of the defect appeared to impact the amount of bubble states that formed.
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